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Modest Elevation in BNP in Asymptomatic Hypertensive Patients Reflects Sub-Clinical Cardiac Remodeling, Inflammation and Extracellular Matrix Changes

In asymptomatic subjects B-type natriuretic peptide (BNP) is associated with adverse cardiovascular outcomes even at levels well below contemporary thresholds used for the diagnosis of heart failure. The mechanisms behind these observations are unclear. We examined the hypothesis that in an asymptom...

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Detalles Bibliográficos
Autores principales: Phelan, Dermot, Watson, Chris, Martos, Ramon, Collier, Patrick, Patle, Anil, Donnelly, Seamas, Ledwidge, Mark, Baugh, John, McDonald, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495762/
https://www.ncbi.nlm.nih.gov/pubmed/23152884
http://dx.doi.org/10.1371/journal.pone.0049259