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IL-12p40 Deficiency Leads to Uncontrolled Trypanosoma cruzi Dissemination in the Spinal Cord Resulting in Neuronal Death and Motor Dysfunction

Chagas’ disease is a protozoosis caused by Trypanosoma cruzi that frequently shows severe chronic clinical complications of the heart or digestive system. Neurological disorders due to T. cruzi infection are also described in children and immunosuppressed hosts. We have previously reported that IL-1...

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Detalles Bibliográficos
Autores principales: Bombeiro, André Luis, Gonçalves, Lígia Antunes, Penha-Gonçalves, Carlos, Marinho, Claudio Romero Farias, D’Império Lima, Maria Regina, Chadi, Gerson, Álvarez, José Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495776/
https://www.ncbi.nlm.nih.gov/pubmed/23152844
http://dx.doi.org/10.1371/journal.pone.0049022