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IL-12p40 Deficiency Leads to Uncontrolled Trypanosoma cruzi Dissemination in the Spinal Cord Resulting in Neuronal Death and Motor Dysfunction
Chagas’ disease is a protozoosis caused by Trypanosoma cruzi that frequently shows severe chronic clinical complications of the heart or digestive system. Neurological disorders due to T. cruzi infection are also described in children and immunosuppressed hosts. We have previously reported that IL-1...
Autores principales: | Bombeiro, André Luis, Gonçalves, Lígia Antunes, Penha-Gonçalves, Carlos, Marinho, Claudio Romero Farias, D’Império Lima, Maria Regina, Chadi, Gerson, Álvarez, José Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495776/ https://www.ncbi.nlm.nih.gov/pubmed/23152844 http://dx.doi.org/10.1371/journal.pone.0049022 |
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