BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors

BACKGROUND: As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their possible implication, the aim of this study...

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Detalles Bibliográficos
Autores principales: Boeuf, Stephane, Bovée, Judith VMG, Lehner, Burkhard, van den Akker, Brendy, van Ruler, Maayke, Cleton-Jansen, Anne-Marie, Richter, Wiltrud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495847/
https://www.ncbi.nlm.nih.gov/pubmed/23088614
http://dx.doi.org/10.1186/1471-2407-12-488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495847/
https://www.ncbi.nlm.nih.gov/pubmed/23088614
http://dx.doi.org/10.1186/1471-2407-12-488

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