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BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors
BACKGROUND: As major regulators of normal chondrogenesis, the bone morphogenic protein (BMP) and transforming growth factor β (TGFB) signaling pathways may be involved in the development and progression of central chondrosarcoma. In order to uncover their possible implication, the aim of this study...
Autores principales: | Boeuf, Stephane, Bovée, Judith VMG, Lehner, Burkhard, van den Akker, Brendy, van Ruler, Maayke, Cleton-Jansen, Anne-Marie, Richter, Wiltrud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495847/ https://www.ncbi.nlm.nih.gov/pubmed/23088614 http://dx.doi.org/10.1186/1471-2407-12-488 |
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