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Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma

BACKGROUND: Alterations of mTOR gene expression have been implicated in the pathogenesis of endometrioid endometrial cancer however only few studies explored the cause of increased mTOR activation in this malignancy. miRNAs are small, noncoding RNAs, which were proven to regulated gene expression at...

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Detalles Bibliográficos
Autores principales: Torres, Anna, Torres, Kamil, Pesci, Anna, Ceccaroni, Marcello, Paszkowski, Tomasz, Cassandrini, Paola, Zamboni, Giuseppe, Maciejewski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495850/
https://www.ncbi.nlm.nih.gov/pubmed/22920721
http://dx.doi.org/10.1186/1471-2407-12-369