Anthrax Lethal Factor Cleaves Mouse Nlrp1b in Both Toxin-Sensitive and Toxin-Resistant Macrophages

Anthrax lethal factor (LF) is the protease component of anthrax lethal toxin (LT). LT induces pyroptosis in macrophages of certain inbred mouse and rat strains, while macrophages from other inbred strains are resistant to the toxin. In rats, the sensitivity of macrophages to toxin-induced cell death...

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Detalles Bibliográficos
Autores principales: Hellmich, Kristina A., Levinsohn, Jonathan L., Fattah, Rasem, Newman, Zachary L., Maier, Nolan, Sastalla, Inka, Liu, Shihui, Leppla, Stephen H., Moayeri, Mahtab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495862/
https://www.ncbi.nlm.nih.gov/pubmed/23152930
http://dx.doi.org/10.1371/journal.pone.0049741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495862/
https://www.ncbi.nlm.nih.gov/pubmed/23152930
http://dx.doi.org/10.1371/journal.pone.0049741

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