Cargando…
Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains
Ionotropic glutamate receptors (iGluRs) harbor two extracellular domains: the membrane-proximal ligand-binding domain (LBD) and the distal N-terminal domain (NTD). These are involved in signal sensing: the LBD binds L-glutamate, which activates the receptor channel. Ligand binding to the NTD modulat...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496038/ https://www.ncbi.nlm.nih.gov/pubmed/22959625 http://dx.doi.org/10.1016/j.str.2012.08.012 |