Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains

Ionotropic glutamate receptors (iGluRs) harbor two extracellular domains: the membrane-proximal ligand-binding domain (LBD) and the distal N-terminal domain (NTD). These are involved in signal sensing: the LBD binds L-glutamate, which activates the receptor channel. Ligand binding to the NTD modulat...

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Detalles Bibliográficos
Autores principales: Dutta, Anindita, Shrivastava, Indira H., Sukumaran, Madhav, Greger, Ingo H., Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496038/
https://www.ncbi.nlm.nih.gov/pubmed/22959625
http://dx.doi.org/10.1016/j.str.2012.08.012

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