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Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity
Smad proteins are the key intermediates of transforming growth factor-beta (TGF-β) signaling during development and in tissue homeostasis. Pertubations in TGF-β/Smad signaling have been implicated in cancer and other diseases. In the cell nucleus, Smad complexes trigger cell type- and context-specif...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496114/ https://www.ncbi.nlm.nih.gov/pubmed/22315972 http://dx.doi.org/10.1186/bcr3066 |