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Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticity

Smad proteins are the key intermediates of transforming growth factor-beta (TGF-β) signaling during development and in tissue homeostasis. Pertubations in TGF-β/Smad signaling have been implicated in cancer and other diseases. In the cell nucleus, Smad complexes trigger cell type- and context-specif...

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Detalles Bibliográficos
Autores principales:	Sundqvist, Anders, ten Dijke, Peter, van Dam, Hans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496114/ https://www.ncbi.nlm.nih.gov/pubmed/22315972 http://dx.doi.org/10.1186/bcr3066

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