Hyperinsulinemia enhances c-Myc-mediated mammary tumor development and advances metastatic progression to the lung in a mouse model of type 2 diabetes

INTRODUCTION: Hyperinsulinemia, which is common in early type 2 diabetes (T2D) as a result of the chronically insulin-resistant state, has now been identified as a specific factor which can worsen breast cancer prognosis. In breast cancer, a high rate of mortality persists due to the emergence of pu...

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Detalles Bibliográficos
Autores principales: Ferguson, Rosalyn D, Novosyadlyy, Ruslan, Fierz, Yvonne, Alikhani, Nyosha, Sun, Hui, Yakar, Shoshana, LeRoith, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496123/
https://www.ncbi.nlm.nih.gov/pubmed/22226054
http://dx.doi.org/10.1186/bcr3089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496123/
https://www.ncbi.nlm.nih.gov/pubmed/22226054
http://dx.doi.org/10.1186/bcr3089

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