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STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas
INTRODUCTION: Although breast cancers expressing estrogen receptor-α (ERα) and progesterone receptors (PR) are the most common form of mammary malignancy in humans, it has been difficult to develop a suitable mouse model showing similar steroid hormone responsiveness. STAT transcription factors play...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496133/ https://www.ncbi.nlm.nih.gov/pubmed/22264274 http://dx.doi.org/10.1186/bcr3100 |