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STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

INTRODUCTION: Although breast cancers expressing estrogen receptor-α (ERα) and progesterone receptors (PR) are the most common form of mammary malignancy in humans, it has been difficult to develop a suitable mouse model showing similar steroid hormone responsiveness. STAT transcription factors play...

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Detalles Bibliográficos
Autores principales: Chan, Szeman Ruby, Vermi, William, Luo, Jingqin, Lucini, Laura, Rickert, Charles, Fowler, Amy M, Lonardi, Silvia, Arthur, Cora, Young, Larry JT, Levy, David E, Welch, Michael J, Cardiff, Robert D, Schreiber, Robert D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496133/
https://www.ncbi.nlm.nih.gov/pubmed/22264274
http://dx.doi.org/10.1186/bcr3100