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STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas
INTRODUCTION: Although breast cancers expressing estrogen receptor-α (ERα) and progesterone receptors (PR) are the most common form of mammary malignancy in humans, it has been difficult to develop a suitable mouse model showing similar steroid hormone responsiveness. STAT transcription factors play...
Autores principales: | Chan, Szeman Ruby, Vermi, William, Luo, Jingqin, Lucini, Laura, Rickert, Charles, Fowler, Amy M, Lonardi, Silvia, Arthur, Cora, Young, Larry JT, Levy, David E, Welch, Michael J, Cardiff, Robert D, Schreiber, Robert D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496133/ https://www.ncbi.nlm.nih.gov/pubmed/22264274 http://dx.doi.org/10.1186/bcr3100 |
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