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Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma

INTRODUCTION: GP88 (progranulin) has been implicated in tumorigenesis and resistance to anti-estrogen therapies for estrogen receptor positive (ER(+)) breast cancer. Previous pathological studies showed that GP88 is expressed in invasive ductal carcinoma (IDC), but not in normal mammary epithelial t...

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Detalles Bibliográficos
Autores principales: Serrero, Ginette, Hawkins, Douglas M, Yue, Binbin, Ioffe, Olga, Bejarano, Pablo, Phillips, Jeffrey T, Head, Jonathan F, Elliott, Robert L, Tkaczuk, Katherine R, Godwin, Andrew K, Weaver, JoEllen, Kim, Wes E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496144/
https://www.ncbi.nlm.nih.gov/pubmed/22316048
http://dx.doi.org/10.1186/bcr3111