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PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups
INTRODUCTION: PIK3CA is the oncogene showing the highest frequency of gain-of-function mutations in breast cancer, but the prognostic value of PIK3CA mutation status is controversial. METHODS: We investigated the prognostic significance of PIK3CA mutation status in a series of 452 patients with unil...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496146/ https://www.ncbi.nlm.nih.gov/pubmed/22330809 http://dx.doi.org/10.1186/bcr3113 |