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Limited significance of family history for presence of BRCA1 gene mutation in Polish breast and ovarian cancer cases
It is estimated that about 5–10% of ovarian and 2–5% of all breast cancer patients are carriers of a germline BRCA1 or BRCA2 gene mutation. Most families with detected BRCA1 or BRCA2 gene mutation are qualified for molecular testing on the basis of family history of breast or ovarian cancers. The pu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496543/ https://www.ncbi.nlm.nih.gov/pubmed/22395474 http://dx.doi.org/10.1007/s10689-012-9519-5 |