The effects of sodium diethyldithiocarbamate in fibroblasts V79 cells in relation to cytotoxicity, antioxidative enzymes, glutathione, and apoptosis

Sodium diethyldithiocarbamate (DETC) is the main metabolite of disulfiram. Recently, we reported that mechanism of disulfiram cytotoxicity in V79 cells might be partially connected with thiol redox-state imbalance. Here, we examined the effect of DETC on the level of intracellular glutathione (GSH),...

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Detalles Bibliográficos
Autores principales: Rahden-Staroń, I., Grosicka-Maciąg, E., Kurpios-Piec, D., Czeczot, H., Grzela, T., Szumiło, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Molecular Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496549/
https://www.ncbi.nlm.nih.gov/pubmed/22872140
http://dx.doi.org/10.1007/s00204-012-0909-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496549/
https://www.ncbi.nlm.nih.gov/pubmed/22872140
http://dx.doi.org/10.1007/s00204-012-0909-0

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