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Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival
Neurons are post-mitotic cells that undergo an active downregulation of cell cycle-related proteins to survive. The activity of the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase that regulates cell cycle progression in proliferating cells, plays a relevant role in post-mitotic...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Humana Press Inc
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496556/ https://www.ncbi.nlm.nih.gov/pubmed/22836916 http://dx.doi.org/10.1007/s12035-012-8309-2 |