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Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival

Neurons are post-mitotic cells that undergo an active downregulation of cell cycle-related proteins to survive. The activity of the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase that regulates cell cycle progression in proliferating cells, plays a relevant role in post-mitotic...

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Detalles Bibliográficos
Autor principal: Almeida, Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496556/
https://www.ncbi.nlm.nih.gov/pubmed/22836916
http://dx.doi.org/10.1007/s12035-012-8309-2

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