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Synthesis of hapten and preparation of specific polyclonal antibody with high affinity for lenalidomide, the potent drug for treatment of multiple myeloma

BACKGROUND: For therapeutic monitoring and pharmacokinetic studies of lenalidomide (LND), the potent drug for treatment of multiple myeloma (MM), a specific antibody was required for the development of a sensitive immunoassay system for the accurate determination of LND in plasma. RESULTS: In this s...

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Detalles Bibliográficos
Autores principales: Darwish, Ibrahim A, Alzoman, Nourh Z, Abuhejail, Reem M, El-Samani, Tilal E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496571/
https://www.ncbi.nlm.nih.gov/pubmed/23101764
http://dx.doi.org/10.1186/1752-153X-6-125