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Accelerated maximum likelihood parameter estimation for stochastic biochemical systems

BACKGROUND: A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data is still a bottleneck for obtaining accurate simulation results. Many...

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Detalles Bibliográficos
Autores principales: Daigle, Bernie J, Roh, Min K, Petzold, Linda R, Niemi, Jarad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496601/
https://www.ncbi.nlm.nih.gov/pubmed/22548918
http://dx.doi.org/10.1186/1471-2105-13-68