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Accelerated maximum likelihood parameter estimation for stochastic biochemical systems
BACKGROUND: A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data is still a bottleneck for obtaining accurate simulation results. Many...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496601/ https://www.ncbi.nlm.nih.gov/pubmed/22548918 http://dx.doi.org/10.1186/1471-2105-13-68 |