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Accelerated maximum likelihood parameter estimation for stochastic biochemical systems

BACKGROUND: A prerequisite for the mechanistic simulation of a biochemical system is detailed knowledge of its kinetic parameters. Despite recent experimental advances, the estimation of unknown parameter values from observed data is still a bottleneck for obtaining accurate simulation results. Many...

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Detalles Bibliográficos
Autores principales:	Daigle, Bernie J, Roh, Min K, Petzold, Linda R, Niemi, Jarad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496601/ https://www.ncbi.nlm.nih.gov/pubmed/22548918 http://dx.doi.org/10.1186/1471-2105-13-68

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