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The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

Intracellular survival of Salmonella relies on the activity of proteins translocated into the host cell by type III secretion systems (T3SS). The protein kinase activity of the T3SS effector SteC is required for F-actin remodeling in host cells, although no SteC target has been identified so far. He...

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Detalles Bibliográficos
Autores principales: Fernandez-Piñar, Pablo, Alemán, Ainel, Sondek, John, Dohlman, Henrik G., Molina, María, Martín, Humberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496616/
https://www.ncbi.nlm.nih.gov/pubmed/23015760
http://dx.doi.org/10.1091/mbc.E12-03-0243