Cargando…

The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

Intracellular survival of Salmonella relies on the activity of proteins translocated into the host cell by type III secretion systems (T3SS). The protein kinase activity of the T3SS effector SteC is required for F-actin remodeling in host cells, although no SteC target has been identified so far. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernandez-Piñar, Pablo, Alemán, Ainel, Sondek, John, Dohlman, Henrik G., Molina, María, Martín, Humberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496616/ https://www.ncbi.nlm.nih.gov/pubmed/23015760 http://dx.doi.org/10.1091/mbc.E12-03-0243

Ejemplares similares

The Borg family of Cdc42 effector proteins Cdc42EP1–5
por: Farrugia, Aaron J., et al.
Publicado: (2016)

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae
Publicado: (1990)

Cdc42 Effector Protein 3 Interacts With Cdc42 in Regulating Xenopus Somite Segmentation
por: Kho, Mary, et al.
Publicado: (2019)

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity
Publicado: (1990)

The evolutionary history of effectors downstream of Cdc42 and Rac
por: Cotteret, Sophie, et al.
Publicado: (2002)

Nucleocytoplasmic Shuttling of the Cdc42p Exchange Factor Cdc24p
por: Nern, Aljoscha, et al.
Publicado: (2000)

A Novel Function of Saccharomyces cerevisiae CDC5 in Cytokinesis
por: Song, Sukgil, et al.
Publicado: (2001)

SteC is a Salmonella kinase required for SPI-2-dependent F-actin remodelling
por: Poh, John, et al.
Publicado: (2008)

The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton
por: Odendall, Charlotte, et al.
Publicado: (2012)

Distinct Roles of Cdc42 in Thymopoiesis and Effector and Memory T Cell Differentiation
por: Guo, Fukun, et al.
Publicado: (2011)

The CDC42 effector protein MRCKβ autophosphorylates on Threonine 1108
por: Unbekandt, Mathieu, et al.
Publicado: (2019)

Cdc42 regulates Cdc42EP3 function in cancer-associated fibroblasts
por: Farrugia, Aaron J., et al.
Publicado: (2016)

Cdc42 turns the spindle
por: Leslie, Mitch
Publicado: (2008)

The first buds of Cdc42
por: Short, Ben
Publicado: (2015)

Secretory Vesicles Deliver Cdc42p to Sites of Polarized Growth in S. cerevisiae
por: Dighe, Shubha A., et al.
Publicado: (2014)

Identification of CDC42 Effectors Operating in FGD1-Dependent Trafficking at the Golgi
por: Egorov, Mikhail, et al.
Publicado: (2019)

The Small GTPase Cdc42 Is a Major Regulator of Neutrophil Effector Functions
por: Tackenberg, Heidi, et al.
Publicado: (2020)

Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
por: Jahid, Sohail, et al.
Publicado: (2022)

Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES
por: Watson, Joanna R., et al.
Publicado: (2016)

Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCF(Cdc4) recognition in Saccharomyces cerevisiae
por: Al-Zain, Amr, et al.
Publicado: (2015)

Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae
por: Rossbach, Daniel, et al.
Publicado: (2017)

Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2
por: Höfken, Thomas, et al.
Publicado: (2004)

Regulation of dendrite growth by Cdc42 effector protein-4 in hippocampal neurons in vitro
por: Hou, Lei, et al.
Publicado: (2022)

Spatial analysis of Cdc42 activity reveals a role for plasma membrane–associated Cdc42 in centrosome regulation
por: Herrington, Kari A., et al.
Publicado: (2017)

The Cdc42 effectors Gic1 and Gic2 regulate polarized post-Golgi secretion
por: Liu, Ying, et al.
Publicado: (2019)

A Role for Cdc42 in Macrophage Chemotaxis
por: Allen, William E., et al.
Publicado: (1998)

Cdc42 and Tinman march to the same beat
por: Short, Ben
Publicado: (2011)

Ubiquitin-dependent regulation of Cdc42 by XIAP
por: Murali, Arun, et al.
Publicado: (2017)

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction
por: Verboon, Jeffrey M., et al.
Publicado: (2020)

Molecular subversion of Cdc42 signalling in cancer
por: Murphy, Natasha P., et al.
Publicado: (2021)

Progress in the therapeutic inhibition of Cdc42 signalling
por: Murphy, Natasha P., et al.
Publicado: (2021)

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
por: Philip, Jasmin, et al.
Publicado: (2022)

Roles of the CDC24 gene product in cellular morphogenesis during the Saccharomyces cerevisiae cell cycle
Publicado: (1981)

Deletion of MEC1 suppresses the replicative senescence of the cdc13-2 mutant in Saccharomyces cerevisiae
por: Yao, Yue, et al.
Publicado: (2023)

Functional Characterization and Cellular Dynamics of the CDC-42 – RAC – CDC-24 Module in Neurospora crassa
por: Araujo-Palomares, Cynthia L., et al.
Publicado: (2011)

Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG
por: Fukuhara, Tatsuro, et al.
Publicado: (2004)

RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42
por: Misselwitz, Benjamin, et al.
Publicado: (2011)

The Exo70 Subunit of the Exocyst Is an Effector for Both Cdc42 and Rho3 Function in Polarized Exocytosis
por: Wu, Hao, et al.
Publicado: (2010)

Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis
por: Duan, Xin, et al.
Publicado: (2021)

A Synthetic Interaction between CDC20 and RAD4 in Saccharomyces cerevisiae upon UV Irradiation
por: Connors, Bernadette, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m78i4kcg0ft7s324ichv1cduol