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The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer

Leukotrienes (LTs) are lipid-signaling molecules derived from arachidonic acid (AA) that initiate and amplify inflammation. To initiate LT formation, the 5-lipoxygenase (5-LO) enzyme translocates to nuclear membranes, where it associates with its scaffold protein, 5-lipoxygenase–activating protein (...

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Detalles Bibliográficos
Autores principales: Bair, Angela M., Turman, Melissa V., Vaine, Christine A., Panettieri, Reynold A., Soberman, Roy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496618/
https://www.ncbi.nlm.nih.gov/pubmed/23015755
http://dx.doi.org/10.1091/mbc.E12-06-0489