Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis

BACKGROUND: Hepatic dysfunction and jaundice are traditionally viewed as late features of sepsis and portend poor outcomes. We hypothesized that changes in liver function occur early in the onset of sepsis, yet pass undetected by standard laboratory tests. METHODS AND FINDINGS: In a long-term rat mo...

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Detalles Bibliográficos
Autores principales: Recknagel, Peter, Gonnert, Falk A., Westermann, Martin, Lambeck, Sandro, Lupp, Amelie, Rudiger, Alain, Dyson, Alex, Carré, Jane E., Kortgen, Andreas, Krafft, Christoph, Popp, Jürgen, Sponholz, Christoph, Fuhrmann, Valentin, Hilger, Ingrid, Claus, Ralf A., Riedemann, Niels C., Wetzker, Reinhard, Singer, Mervyn, Trauner, Michael, Bauer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496669/
https://www.ncbi.nlm.nih.gov/pubmed/23152722
http://dx.doi.org/10.1371/journal.pmed.1001338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496669/
https://www.ncbi.nlm.nih.gov/pubmed/23152722
http://dx.doi.org/10.1371/journal.pmed.1001338

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