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MicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinoma

BACKGROUND: The enhancer of zeste homolog 2 (EZH2) was found to be overexpressed and associated with tumor metastasis in esophageal squamous cell carcinoma (ESCC). On the other hand, it was reported that miR-26a, miR-98, miR-101, miR-124, miR-138 and miR-214 could inhibit the expression of EZH2 in s...

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Detalles Bibliográficos
Autores principales: Huang, Sheng-Dong, Yuan, Yang, Zhuang, Chong-Wen, Li, Bai-Ling, Gong, De-Jun, Wang, Shu-Gang, Zeng, Zhi-Yong, Cheng, He-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496689/
https://www.ncbi.nlm.nih.gov/pubmed/22867052
http://dx.doi.org/10.1186/1476-4598-11-51