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Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring

BACKGROUND: There is mounting evidence for a neurodevelopmental basis for disorders such as autism and schizophrenia, in which prenatal or early postnatal events may influence brain development and predispose the young to develop these and related disorders. We have now investigated the effect of a...

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Detalles Bibliográficos
Autores principales: Forrest, Caroline M, Khalil, Omari S, Pisar, Mazura, Smith, Robert A, Darlington, Lynda Gail, Stone, Trevor W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496691/
https://www.ncbi.nlm.nih.gov/pubmed/22681877
http://dx.doi.org/10.1186/1756-6606-5-22