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Prenatal activation of Toll-like receptors-3 by administration of the viral mimetic poly(I:C) changes synaptic proteins, N-methyl-D-aspartate receptors and neurogenesis markers in offspring
BACKGROUND: There is mounting evidence for a neurodevelopmental basis for disorders such as autism and schizophrenia, in which prenatal or early postnatal events may influence brain development and predispose the young to develop these and related disorders. We have now investigated the effect of a...
Autores principales: | Forrest, Caroline M, Khalil, Omari S, Pisar, Mazura, Smith, Robert A, Darlington, Lynda Gail, Stone, Trevor W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496691/ https://www.ncbi.nlm.nih.gov/pubmed/22681877 http://dx.doi.org/10.1186/1756-6606-5-22 |
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