Substrate Mediated Enzyme Prodrug Therapy

In this report, we detail Substrate Mediated Enzyme Prodrug Therapy (SMEPT) as a novel approach in drug delivery which relies on enzyme-functionalized cell culture substrates to achieve a localized conversion of benign prodrug(s) into active therapeutics with subsequent delivery to adhering cells or...

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Detalles Bibliográficos
Autores principales: Fejerskov, Betina, Zelikin, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496709/
https://www.ncbi.nlm.nih.gov/pubmed/23152927
http://dx.doi.org/10.1371/journal.pone.0049619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496709/
https://www.ncbi.nlm.nih.gov/pubmed/23152927
http://dx.doi.org/10.1371/journal.pone.0049619

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