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Substrate Mediated Enzyme Prodrug Therapy
In this report, we detail Substrate Mediated Enzyme Prodrug Therapy (SMEPT) as a novel approach in drug delivery which relies on enzyme-functionalized cell culture substrates to achieve a localized conversion of benign prodrug(s) into active therapeutics with subsequent delivery to adhering cells or...
Autores principales: | Fejerskov, Betina, Zelikin, Alexander N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496709/ https://www.ncbi.nlm.nih.gov/pubmed/23152927 http://dx.doi.org/10.1371/journal.pone.0049619 |
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