An Efficient Kinetic Model for Assemblies of Amyloid Fibrils and Its Application to Polyglutamine Aggregation

Protein polymerization consists in the aggregation of single monomers into polymers that may fragment. Fibrils assembly is a key process in amyloid diseases. Up to now, protein aggregation was commonly mathematically simulated by a polymer size-structured ordinary differential equations (ODE) system...

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Detalles Bibliográficos
Autores principales: Prigent, Stéphanie, Ballesta, Annabelle, Charles, Frédérique, Lenuzza, Natacha, Gabriel, Pierre, Tine, Léon Matar, Rezaei, Human, Doumic, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496744/
https://www.ncbi.nlm.nih.gov/pubmed/23152746
http://dx.doi.org/10.1371/journal.pone.0043273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496744/
https://www.ncbi.nlm.nih.gov/pubmed/23152746
http://dx.doi.org/10.1371/journal.pone.0043273

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