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Vixapatin (VP12), a C-Type Lectin-Protein from Vipera xantina palestinae Venom: Characterization as a Novel Anti-angiogenic Compound

A C-type lectin-like protein (CTL), originally identified as VP12 and lately named Vixapatin, was isolated and characterized from Israeli viper Vipera xantina palestinae snake venom. This CTL was characterized as a selective α2β1 integrin inhibitor with anti-melanoma metastatic activity. The major a...

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Detalles Bibliográficos
Autores principales: Momic, Tatjana, Cohen, Gadi, Reich, Reuven, Arlinghaus, Franziska T., Eble, Johannes A., Marcinkiewicz, Cezary, Lazarovici, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496993/
https://www.ncbi.nlm.nih.gov/pubmed/23162702
http://dx.doi.org/10.3390/toxins4100862