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Vixapatin (VP12), a C-Type Lectin-Protein from Vipera xantina palestinae Venom: Characterization as a Novel Anti-angiogenic Compound
A C-type lectin-like protein (CTL), originally identified as VP12 and lately named Vixapatin, was isolated and characterized from Israeli viper Vipera xantina palestinae snake venom. This CTL was characterized as a selective α2β1 integrin inhibitor with anti-melanoma metastatic activity. The major a...
Autores principales: | Momic, Tatjana, Cohen, Gadi, Reich, Reuven, Arlinghaus, Franziska T., Eble, Johannes A., Marcinkiewicz, Cezary, Lazarovici, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496993/ https://www.ncbi.nlm.nih.gov/pubmed/23162702 http://dx.doi.org/10.3390/toxins4100862 |
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