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Clinical Uses of Botulinum Neurotoxins: Current Indications, Limitations and Future Developments

Botulinum neurotoxins (BoNTs) cause flaccid paralysis by interfering with vesicle fusion and neurotransmitter release in the neuronal cells. BoNTs are the most widely used therapeutic proteins. BoNT/A was approved by the U.S. FDA to treat strabismus, blepharospam, and hemificial spasm as early as 19...

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Detalles Bibliográficos
Autor principal: Chen, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496996/
https://www.ncbi.nlm.nih.gov/pubmed/23162705
http://dx.doi.org/10.3390/toxins4100913