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Sarcophine-Diol Inhibits Expression of COX-2, Inhibits Activity of cPLA(2), Enhances Degradation of PLA(2) and PLC(γ)1 and Inhibits Cell Membrane Permeability in Mouse Melanoma B(16)F(10) Cells

Sarcophine-diol (SD) is a semi-synthetic derivative of sarcophine with a significant chemopreventive effect against non-melanoma skin cancer both in vitro and in vivo. Recently, we have studied the effect of SD on melanoma development using the mouse melanoma B(16)F(10) cell line. In this study, our...

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Detalles Bibliográficos
Autores principales: Szymanski, Pawel T., Muley, Pratik, Ahmed, Safwat A., Khalifa, Sherief, Fahmy, Hesham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497015/
https://www.ncbi.nlm.nih.gov/pubmed/23170076
http://dx.doi.org/10.3390/md10102166