D471G Mutation in LCMV-NP Affects its Ability to Self-associate and Results in a Dominant Negative Effect in Viral RNA Synthesis

Arenaviruses merit significant interest because several family members are etiological agents of severe hemorrhagic fevers, representing a major burden to public health. Currently, there are no FDA-licensed vaccines against arenaviruses and the only available antiviral therapy is limited to the use...

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Detalles Bibliográficos
Autores principales: Ortiz-Riaño, Emilio, Cheng, Benson Y. H., de la Torre, Juan C., Martínez-Sobrido, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497045/
https://www.ncbi.nlm.nih.gov/pubmed/23202457
http://dx.doi.org/10.3390/v4102137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497045/
https://www.ncbi.nlm.nih.gov/pubmed/23202457
http://dx.doi.org/10.3390/v4102137

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