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Cyclic AMP dynamics in the pancreatic β-cell
Insulin secretion from pancreatic β-cells is tightly regulated by glucose and other nutrients, hormones, and neural factors. The exocytosis of insulin granules is triggered by an elevation of the cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) and is further amplified by cyclic AMP (cAMP). Cyclic AMP...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Informa Healthcare
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497220/ https://www.ncbi.nlm.nih.gov/pubmed/22970724 http://dx.doi.org/10.3109/03009734.2012.724732 |