Cargando…
Cyclic AMP dynamics in the pancreatic β-cell
Insulin secretion from pancreatic β-cells is tightly regulated by glucose and other nutrients, hormones, and neural factors. The exocytosis of insulin granules is triggered by an elevation of the cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) and is further amplified by cyclic AMP (cAMP). Cyclic AMP...
Autor principal: | Tengholm, Anders |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497220/ https://www.ncbi.nlm.nih.gov/pubmed/22970724 http://dx.doi.org/10.3109/03009734.2012.724732 |
Ejemplares similares
-
Cyclic AMP links glucose stimulation to somatostatin secretion in δ-cells
por: Tengholm, Anders
Publicado: (2019) -
Glucose- and Hormone-Induced cAMP Oscillations in α- and β-Cells Within Intact Pancreatic Islets
por: Tian, Geng, et al.
Publicado: (2011) -
Glucose‐induced cAMP elevation in β‐cells involves amplification of constitutive and glucagon‐activated GLP‐1 receptor signalling
por: Shuai, Hongyan, et al.
Publicado: (2021) -
Glucose controls glucagon secretion by directly modulating cAMP in alpha cells
por: Yu, Qian, et al.
Publicado: (2019) -
Ghrelin Attenuates cAMP-PKA Signaling to Evoke Insulinostatic Cascade in Islet β-Cells
por: Dezaki, Katsuya, et al.
Publicado: (2011)