Prognostic and Predictive Roles of KRAS Mutation in Colorectal Cancer

The RAS gene family is among the most studied and best characterized of the known cancer-related genes. Of the three human ras isoforms, KRAS is the most frequently altered gene, with mutations occurring in 17%–25% of all cancers. In particular, approximately 30%–40% of colon cancers harbor a KRAS m...

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Detalles Bibliográficos
Autores principales: Arrington, Amanda K., Heinrich, Eileen L., Lee, Wendy, Duldulao, Marjun, Patel, Supriya, Sanchez, Julian, Garcia-Aguilar, Julio, Kim, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497263/
https://www.ncbi.nlm.nih.gov/pubmed/23202889
http://dx.doi.org/10.3390/ijms131012153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497263/
https://www.ncbi.nlm.nih.gov/pubmed/23202889
http://dx.doi.org/10.3390/ijms131012153

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