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Prognostic and Predictive Roles of KRAS Mutation in Colorectal Cancer
The RAS gene family is among the most studied and best characterized of the known cancer-related genes. Of the three human ras isoforms, KRAS is the most frequently altered gene, with mutations occurring in 17%–25% of all cancers. In particular, approximately 30%–40% of colon cancers harbor a KRAS m...
Autores principales: | Arrington, Amanda K., Heinrich, Eileen L., Lee, Wendy, Duldulao, Marjun, Patel, Supriya, Sanchez, Julian, Garcia-Aguilar, Julio, Kim, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497263/ https://www.ncbi.nlm.nih.gov/pubmed/23202889 http://dx.doi.org/10.3390/ijms131012153 |
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