Short Hairpin RNA (shRNA) Ether à go-go 1 (Eag1) Inhibition of Human Osteosarcoma Angiogenesis via VEGF/PI3K/AKT Signaling

Ether à go-go 1 (Eag1) channel is overexpressed in a variety of cancers but the therapeutic potential of Eag1 in osteosarcoma remains elusive. In this study, we constructed an Ad5-Eag1-shRNA vector and evaluated its efficiency for Eag1 knockdown and its effects on osteosarcoma. Our results showed th...

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Detalles Bibliográficos
Autores principales: Wu, Jin, Wu, Xinyu, Zhong, Daixing, Zhai, Wenliang, Ding, Zhenqi, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497288/
https://www.ncbi.nlm.nih.gov/pubmed/23202914
http://dx.doi.org/10.3390/ijms131012573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497288/
https://www.ncbi.nlm.nih.gov/pubmed/23202914
http://dx.doi.org/10.3390/ijms131012573

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