Overcoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416

MDR (multidrug-resistance) represents a major obstacle to successful cancer chemotherapy and is usually accomplished by overexpression of P-gp (P-glycoprotein). Much effort has been devoted to developing P-gp inhibitors to modulate MDR. However, none of the inhibitors on the market have been success...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Zhi, Feng, Xu, Guangming, Tang, Xiaolei, Lu, Sheng, Wu, Jinhui, Hu, Yiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497725/
https://www.ncbi.nlm.nih.gov/pubmed/22757751
http://dx.doi.org/10.1042/BSR20120020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497725/
https://www.ncbi.nlm.nih.gov/pubmed/22757751
http://dx.doi.org/10.1042/BSR20120020

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