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Bench and mathematical modeling of the effects of breathing a helium/oxygen mixture on expiratory time constants in the presence of heterogeneous airway obstructions

BACKGROUND: Expiratory time constants are used to quantify emptying of the lung as a whole, and emptying of individual lung compartments. Breathing low-density helium/oxygen mixtures may modify regional time constants so as to redistribute ventilation, potentially reducing gas trapping and hyperinfl...

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Detalles Bibliográficos
Autores principales: Martin, Andrew R, Katz, Ira M, Terzibachi, Karine, Gouinaud, Laure, Caillibotte, Georges, Texereau, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497861/
https://www.ncbi.nlm.nih.gov/pubmed/22646835
http://dx.doi.org/10.1186/1475-925X-11-27