TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: A dominant role for Smad-2

The anti-atherogenic cytokine, TGF-β, plays a key role during macrophage foam cell formation by modulating the expression of key genes involved in the control of cholesterol homeostasis. Unfortunately, the molecular mechanisms underlying these actions of TGF-β remain poorly understood. In this study...

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Detalles Bibliográficos
Autores principales: Michael, Daryn R., Salter, Rebecca C., Ramji, Dipak P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497875/
https://www.ncbi.nlm.nih.gov/pubmed/22705205
http://dx.doi.org/10.1016/j.bbadis.2012.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497875/
https://www.ncbi.nlm.nih.gov/pubmed/22705205
http://dx.doi.org/10.1016/j.bbadis.2012.06.002

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