Somatic Mutations of PIK3R1 Promote Gliomagenesis

The phosphoinositide 3-kinase (PI3K) pathway is targeted for frequent alteration in glioblastoma (GBM) and is one of the core GBM pathways defined by The Cancer Genome Atlas. Somatic mutations of PIK3R1 are observed in multiple tumor types, but the tumorigenic activity of these mutations has not bee...

Descripción completa

Detalles Bibliográficos
Autores principales: Quayle, Steven N., Lee, Jennifer Y., Cheung, Lydia W T., Ding, Li, Wiedemeyer, Ruprecht, Dewan, Robert W., Huang-Hobbs, Emmet, Zhuang, Li, Wilson, Richard K., Ligon, Keith L., Mills, Gordon B., Cantley, Lewis C., Chin, Lynda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498106/
https://www.ncbi.nlm.nih.gov/pubmed/23166678
http://dx.doi.org/10.1371/journal.pone.0049466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498106/
https://www.ncbi.nlm.nih.gov/pubmed/23166678
http://dx.doi.org/10.1371/journal.pone.0049466

Ejemplares similares