A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii

Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB). Although the insertion sequence, ISAba1, contributes...

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Detalles Bibliográficos
Autores principales: Sun, Jun-Ren, Perng, Cherng-Lih, Chan, Ming-Chin, Morita, Yuji, Lin, Jung-Chung, Su, Chih-Mao, Wang, Wei-Yao, Chang, Tein-Yao, Chiueh, Tzong-Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498117/
https://www.ncbi.nlm.nih.gov/pubmed/23166700
http://dx.doi.org/10.1371/journal.pone.0049534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498117/
https://www.ncbi.nlm.nih.gov/pubmed/23166700
http://dx.doi.org/10.1371/journal.pone.0049534

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