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A Truncated AdeS Kinase Protein Generated by ISAba1 Insertion Correlates with Tigecycline Resistance in Acinetobacter baumannii
Over-expression of AdeABC efflux pump stimulated continuously by the mutated AdeRS two component system has been found to result in antimicrobial resistance, even tigecycline (TGC) resistance, in multidrug-resistant Acinetobacter baumannii (MRAB). Although the insertion sequence, ISAba1, contributes...
Autores principales: | Sun, Jun-Ren, Perng, Cherng-Lih, Chan, Ming-Chin, Morita, Yuji, Lin, Jung-Chung, Su, Chih-Mao, Wang, Wei-Yao, Chang, Tein-Yao, Chiueh, Tzong-Shi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498117/ https://www.ncbi.nlm.nih.gov/pubmed/23166700 http://dx.doi.org/10.1371/journal.pone.0049534 |
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