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Using Phage and Yeast Display to Select Hundreds of Monoclonal Antibodies: Application to Antigen 85, a Tuberculosis Biomarker

BACKGROUND: Current diagnostic methods for tuberculosis (TB), a major global health challenge that kills nearly two million people annually, are time-consuming and inadequate. During infection a number of bacterial molecules that play a role in the infective process are released and have been propos...

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Detalles Bibliográficos
Autores principales: Ferrara, Fortunato, Naranjo, Leslie A., Kumar, Sandeep, Gaiotto, Tiziano, Mukundan, Harshini, Swanson, Basil, Bradbury, Andrew R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498134/
https://www.ncbi.nlm.nih.gov/pubmed/23166701
http://dx.doi.org/10.1371/journal.pone.0049535